Biolane GLME contains several biologically active components. To clarify, these help to suppress inflammation in arthritic joints. Similarly, they provide building blocks for the repair of damaged cartilage.
Cartilage is the smooth covering on the ends of bones, and serves two major roles:
1. Provides a smooth surface so that bones can glide over one another during joint movement.
2. Acts as a shock absorber during moments of stress on the joint.
As with all body tissues, cartilage is continually being broken down and rebuilt. However, in arthritic joints, inflammatory processes accelerate the break-down of cartilage. Therefore, causing many of the symptoms and joint deformities associated with arthritis.
Biolane GLME can help to reverse the arthritic process by:
• Providing enough raw materials (GAGs) to maintain optimal cartilage synthesis.
• Inhibiting prostaglandin production. Therefore limiting inflammation and the cartilage egradation.
• Containing chondroitin sulphates that may inhibit the catabolic cytokine-initiated degradation of cartilage.
• Modulating the immune response which may help to limit inflammation.
• Reducing apoptosis (programmed cell death) within arthritic joints. Subsequently, this may indicate a shift in the underlying destructive disease process.
• Exerting an antihistamine effect to minimise acute-phase inflammatory responses.
Anti-inflammatory properties of Biolane
The inflammation seen in arthritic joints is a complex process. For instance, it involves both local inflammatory responses and chronic immune responses. Importantly, Biolane GLME has been shown to modify both of these responses. Firstly, it inhibits the production of inflammatory prostaglandins and histamine. As a result, there is a reduction in the swelling and pain,
Secondly, Biolane hinders the accumulation of white blood cells (neutrophils14 and T lymphocytes15) at inflammatory sites. To clarify, neutrophils contribute to the inflammatory response by stimulating the release of inflammatory mediators. Similarly, T lymphocytes are important mediators in tissue destruction.